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*Equal contribution †Co-corresponding author
Postdoctoral Work
Myelin pathology is a key feature of X-linked Dystonia Parkinsonism
Priya Prakash†, Kerry C. Limberg*, Weimin Zhang*, Yu Zhao, Klaudia F. Laborc, Anna O'Keeffe, Heather Appleby, Bryanna C. Vilnaigre, Michael R. O'Dea, Cara Fernandez-Cerado, Gierold Paul A. Legarda, Michelle Sy, Edwin L. Munoz, Mark Angelo C. Ang, Cid Czarina E. Diesta, Justin Han, Ean Norenberg, Ellen B. Penney, D. Cristopher Bragg, Adam C. Mar, Ran Brosh, Jef D. Boeke, Shane A. Liddelow†
bioRxiv, 2025
Advances in the genetics and pathology of Lewy body dementia
Sonja W Scholz, Njideka U Okubadejo, Priya Prakash, Shane A Liddelow, Mina Ryten, Glenda M Halliday
The Lancet Neurology, vol. 24(12), 2025, pp. 1026-1037
Genome writing to dissect consequences of SVA retrotransposon disease X-Linked Dystonia Parkinsonism
Weimin Zhang, Yu Zhao*, Priya Prakash*, Heather L. Appleby, Kelly Barriball, Simona Capponi, Qingwen Jiang, Aleksandra M. Wudzinska, Christine A. Vaine, Gwen Ellis, Neha Rahman, Stefan Markovic, Orin Mishkit, Kerry C. Limberg, Matthew T. Maurano, Youssef Z. Wadghiri, Sang Yong Kim, H. T. Marc Timmers, D. Cristopher Bragg, Shane A. Liddelow, Ran Brosh, Jef D. Boeke
bioRxiv, 2025
Single-cell analysis of the nervous system at small and large scales with instant partitions
Paul W. Frazel, K. Fricano-Kugler, Aaron A. May-Zhang, Michael R. O’Dea, Priya Prakash, NM Desmet, H. Lee, Rhoda Meltzer, KM Fontanez, P. Hettige, Y. Agam, G. Lithwick-Yanai, D. Lipson, BW Luikart, Jeremy D. Dasen, Shane A. Liddelow
bioRxiv, 2023
Transplanted astrocytes show functional flexibility in the recipient brain
Paul W. Frazel, Priya Prakash
Journal of Neuroscience, 2023
Proteomic profiling of interferon-responsive reactive astrocytes in rodent and human
Priya Prakash†, Hediye Erdjument-Bromage, Michael R. O’Dea, Christy N. Munson, David Labib, Valentina Fossati, Thomas A. Neubert, Shane A. Liddelow†
Glia, 2023
David Labib, Zhen Wang, Priya Prakash, Matthew Zimmer, Matthew D. Smith, Paul Frazel, Lilianne Barbar, Maria L. Sapar, Peter A. Calabresi, Junmin Peng, Shane A. Liddelow, Valentina Fossati
Frontiers in Molecular Neuroscience, 2022
PhD Work
Lipids: Emerging Players of Microglial Biology.
Priya Prakash†, Caitlin E Randolph, Katherine A Walker, Gaurav Chopra†
Glia, 2025
Priya Prakash*, Palak Manchanda*, Evi Paouri, Kanchan Bisht, Kaushik Sharma, Jitika Rajpoot, Victoria Wendt, Ahad Hossain, Prageeth R Wijewardhane, Caitlin E Randolph, Yihao Chen, Sarah Stanko, Nadia Gasmi, Anxhela Gjojdeshi, Sophie Card, Jonathan Fine, Krupal P Jethava, Matthew G Clark, Bin Dong, Seohee Ma, Alexis Crockett, Elizabeth A Thayer, Marlo Nicolas, Ryann Davis, Dhruv Hardikar, Daniela Allende, Richard A Prayson, Chi Zhang, Dimitrios Davalos, Gaurav Chopra
Immunity, 2025
Krupal P. Jethava*, Priya Prakash*, Palak Manchanda, Harshit Arora, Gaurav Chopra
ChemBioChem, 2022
Neurotoxic reactive astrocytes induce cell death via saturated lipids
Kevin A. Guttenplan, Maya K. Weigel*, Priya Prakash*, Prageeth R. Wijewardhane, Philip Hasel, Uriel A Rufen-Blanchette, Alexandra E. Münch, Jacob A. Blum, Jonathan A Fine, Mikaela C. Neal, Kimberly Bruce, Aaron Gitler, Gaurav Chopra, Shane A. Liddelow, Ben Barres
Nature, 2021
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Priya Prakash*, Krupal P. Jethava*, Nils Korte*, Pablo Izquierdo*, Emilia Favuzzi, Indigo V. L. Rose, Kevin A. Guttenplan, Sayan Dutta, Jean-Christophe Rochet, Gordon Fishell, Shane A. Liddelow, David Attwell, Gaurav Chopra
Chemical Science, 2021
Priya Prakash*, Travis C. Lantz*, Krupal P. Jethava, Gaurav Chopra
Methods and Protocols, 2019