Myelin pathology is a key feature of X-linked Dystonia Parkinsonism

---

Priya Prakash†, Kerry C. Limberg*, Weimin Zhang*, Yu Zhao, Klaudia F. Laborc, Anna O'Keeffe, Heather Appleby, Bryanna C. Vilnaigre, Michael R. O'Dea, Cara Fernandez-Cerado, Gierold Paul A. Legarda, Michelle Sy, Edwin L. Munoz, Mark Angelo C. Ang, Cid Czarina E. Diesta, Justin Han, Ean Norenberg, Ellen B. Penney, D. Cristopher Bragg, Adam C. Mar, Ran Brosh, Jef D. Boeke, Shane A. Liddelow†

bioRxiv, 2025

Genome writing to dissect consequences of SVA retrotransposon disease X-Linked Dystonia Parkinsonism

---

Weimin Zhang, Yu Zhao*, Priya Prakash*, Heather L. Appleby, Kelly Barriball, Simona Capponi, Qingwen Jiang, Aleksandra M. Wudzinska, Christine A. Vaine, Gwen Ellis, Neha Rahman, Stefan Markovic, Orin Mishkit, Kerry C. Limberg, Matthew T. Maurano, Youssef Z. Wadghiri, Sang Yong Kim, H. T. Marc Timmers, D. Cristopher Bragg, Shane A. Liddelow, Ran Brosh, Jef D. Boeke

bioRxiv, 2025